How would your characters get along with characters from other worlds?

I have some fandom characters and some non-fandom characters. It actually depends on which characters from which world they're meeting. For example, I have two witches and one normal human ( three of my non-fandom characters), and I believe they'll get along nicely with some of the characters from the Harry Potter world. Obviously they're going to have some conflict with other characters from the HP world, but I do like some drama, so I don't mind much.