This is an amazing game that you can go crazy with. It's hard to explain… so here's my examples:
Pirates of the Caribbean: Pirate dude is apparently immortal, and he doesn't care if he kills the entire freaking universe.
Epic: The forest gets the bubonic plague.
Pixels: The US Army is trained to play video games and kill centipedes.
Night at the Museum: Grown man's only friends are not only not real, they force him to become nocturnal.
Cloudy With A Chance Of Meatballs: The world food crisis is averted.
Sorcerer's Apprentice: Strange random dude fights strange people, such as a half-naked guy with a pet metal dragon, a Russian guy without the faintest trace of an accent, and a sorceress who sits in fountains so she can blow up the world.
So yeah. There you go.
Have fun!